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However, STING-deficient mice exhibited elevated levels of anti-CII IgG and IgG2c after three weeks of the first immunization

In brief, gRNA to the mouse Insr gene, a donor vector containing loxP sites, and Cas9 mRNA were coinjected into fertilized mouse eggs to generate targeted conditional knockout offspring

Plain sterile water is acceptable only for single-use experiments because there is no preservative for the multi-week draw window

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