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The compound's selectivity extends to its membrane permeability characteristics, which allow efficient cellular uptake without affecting membrane integrity or cellular viability up to 100 M concentrations

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Critically, these effects were absent in 3-AR knockout mice, indicating that an intact 3-AR pathway is required for the lipolytic activity

At that time, CMS adopted the new CPT codes for use under the OPPS, where payment calculations did not suffer from the same problems