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Sessions consisted of repeated individual trials where the animals received a single one-gram food pellet upon three consecutive lever presses (fixed ratio 3 reinforcement schedule, FR3) per trial (see Fig

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Patients should report persistent or worsening symptoms to their provider rather than assuming symptoms will resolve immediately after the drug leaves the body

Nausea usually peaks in the first few days after a dose increase and improves within one to two weeks as your body adjusts