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Excessive intake of acetaminophen results in the formation of a toxic metabolite, NAPQI, which depletes GSH reserves

While formal clinical trials in humans are limited and the compound is not FDA-approved, early preclinical studies and anecdotal reports suggest it may play a role in supporting the body's natural healing processes

Thus, these post marketing data may be useful to complement findings from other study designs, but cannot be safely interpreted in isolation

The rats in individual groups (n = 3 per group) were anesthetized intraperitoneally with pentobarbital

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