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It is impossible for any of us to be immune from the knowledge of what panoply of risks smoking entails, nor how horribly antisocial a habit an affluent, liberal and powerful tranche of the population consider it to be

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For lung cancer, some case-control studies found no dose-response gradient after tobacco adjustment (8), whereas others reported elevated risks with heavy cannabis use (84), and MR studies suggest a potential causal link, particularly with squamous histology (65,66)

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