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Fatty acid synthase inhibition with Orlistat promotes apoptosis and reduces cell growth and lymph node metastasis in a mouse melanoma model

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The analytical column was placed inside the Column Toaster (Bruker) and its emitter side was installed inside the CaptiveSpray ion source (Bruker) according to the manufacturer instructions with the column temperature set to 50 C

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The process of aerobic oxidation in tumor cells is a complex metabolic pathway that involves the expression of various enzymes and is finely regulated by multiple signaling molecules