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7 So, the half-life of a drug that is metabolized by CYP2D6 would depend on the metabolic status of the individual
The TH gene is located on chromosome 11p15.5 and is composed of 14 exons that generate three alternatively spliced mRNAs that encode tyrosine hydroxylase isoform a (528 amino acids), isoform b (497 amino acids), and isoform c (524 amino acids)
142 : 8088 Marcus DL, de Leon MJ, Goldman J, Logan J, Christman DR, Wolf AP et al
JMIR Formative Research , 6(5), e35706
It originates from either side of the medulla oblongata, exits through the jugular foramen, and descends the neck, chest, and abdomen (Liu and Forsythe, 2021)
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