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This type of cochlear synaptopathy, referred to as hidden hearing loss because the deficits can hide behind a normal audiogram 11 , is posited to trigger neural hyperactivity that underlies tinnitus 19,20,21 , potentially offering a valuable drug target for the development of novel tinnitus treatments

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This is especially true for high-performing professionals, parents, and students trying to juggle mental focus and physical stamina

Conversely to the use of inhibitors, due to the interest in promoting maintenance of NAD + levels in aging and age-associated conditions, the development of NAMPT activators has been the emphasis of recent investigation