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1 Introduction Diabetes mellitus (DM) is a metabolic disease characterized by hyperglycemia (elevated blood glucose), which is caused by a lack of insulin or failure of insulin, resulting in cells being unable to absorb glucose, thus increasing blood glucose levels
There is no universal avoid list, but very greasy, very large, very sugary, or heavily fried meals may worsen nausea or fullness for some people
The primary mechanisms of action include: Enhanced insulin secretion : GLP-1 receptor agonists stimulate glucose-dependent insulin release from pancreatic beta cells, meaning insulin is released only when blood glucose levels are elevated, reducing hypoglycemia risk when used as monotherapy (though risk increases when combined with insulin or sulfonylureas)
The dramatic weight loss achieved with semaglutide and tirzepatide creates unique challenges that differ from traditional weight loss scenarios
Physicians appreciate the dual benefit of these drugs in managing both conditions, which is essential given the rising incidence of diabetes in India
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