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ROS Overproduction: The Initiating Driver Hyperglycaemia activates multiple simultaneous ROS sources, including mitochondrial uncoupling, NADPH oxidase isoforms NOX2 and NOX4, and xanthine oxidase upregulation

Questa affinit quantificata da una costante di stabilit logaritmica pari a 16,44, un valore che supera di gran lunga quello di complessi simili e che giustifica la formazione spontanea del complesso GHK-Cu in ambiente fisiologico

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doi: 10.1080/13543784.2024.2305126