IBS-C patients had lower serum GLP-1 levels, which was connected with abdominal pain, indicating GLP-1s potential for alleviating pain in these patients
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The Cochrane Database of Systematic Reviews (4) CD004514
When the benefit outweighs the side effect, and when it might not For most patients, the metabolic benefits of GLP-1 therapy, including improved cardiovascular risk factors, better insulin sensitivity, reduced visceral fat, and meaningful weight loss, far outweigh a temporary or modest change in libido
When the body is at a lower weight, and you are no longer on the medication, your brain and body prioritize storing fat and see the decrease in calories as a sign of distress, which can mean you may still gain weight even if you continue habits you began while on medication, such as eating smaller portions