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Researchers have also continued to examine whether chronic pancreatic inflammation, recurrent pancreatitis, or prolonged pancreatic injury could contribute to long-term complications involving pancreatic cancer, although current evidence regarding causation remains under ongoing scientific review

While these symptoms often reflect the medication's mechanism of action combined with altered biliary physiology, persistent or severe abdominal pain, vomiting, or signs of jaundice may indicate complications requiring urgent medical attention and discontinuation of semaglutide

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The company stated that the daily, non-peptide oral GLP-1 receptor agonist can be taken anytime without food or water restrictions

That kind of change does not happen without consequences for the musculoskeletal system