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Why Weekends Are the Hardest for Weight Loss For many patients, weekends present the biggest challenge to healthy eating and portion control : Dining out and social gatherings Alcohol consumption Less structure around meals Emotional or stress eating Larger portions and comfort foods If a patient injects on Monday , peak medication effectiveness often aligns with the workweekwhen routines, meal prep, and healthy food choices are easier to maintain

[DOI] [PubMed] [Google Scholar] 18.Kang EA, Han YM, An JM, Park YJ, Sikiric P, Kim DH, Kwon KA, Kim YJ, Yang D, Tchah H, Hahm KB

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Individuals with severe gastroparesis or significant gastrointestinal disease may be at greater risk of exacerbated symptoms and would need careful individual assessment before commencing treatment