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19 Following further translocation to the mitochondria, activated phosphorylated JNK initiates a cascade in which JNK binds to the outer mitochondrial membrane scaffold protein Sab, inhibiting electron transport and thereby increasing the generation of ROS and peroxynitrite

At the molecular level, caspase activation and other chemicals generated by mitochondria regulate apoptosis (Babaeenezhad et al

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Key Differences in Diagnosis and Treatment Understanding the differences between these conditions affects treatment approaches