It is normally diagnosed based on clinical symptomatology complemented by MRI with lesions of various stages, combined with biomarkers of immunologic activity in CSF, namely oligoclonal bands and elevated IgG index (Thompson et al., 2018)
During weight loss, especially rapid weight loss from GLP-1 medications, cells undergo significant stress
EMPA-KIDNEY Collaborative Group, Herrington WG, Staplin N, Wanner C, Green JB, Hauske SJ, et al
Most recently, a 2024 study investigated Mounjaro (tirzepatide) in 62 adults with type 1 diabetes and overweight or obesity
Patients with a history of anorexia nervosa or bulimia nervosa require particularly careful evaluation, as rapid weight loss may not be appropriate