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Additionally, Vitamin C plays a crucial role in maintaining glutathione in its active, reduced state, while adequate levels of B-vitamins (particularly unmethylated B12 and folate) are necessary to support the methylation cycle that drives natural glutathione production

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Methods Search Strategy and Study Selection The Preferred Reporting Items for Systematic Reviews and Meta-Analyses checklist was inspected for the systematic review ( Tables S1, S2 , respectively