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Risk groups: Conditions when Phentermine and Semaglutide are not recommended together or even separately are type-2 diabetes, heart disease, kidney or gallbladder issues, pancreatitis, glaucoma, hyperthyroidism, and medullary thyroid cancer or multiple endocrine neoplasia

The Effects of Supplementation With L-Arginine on Anthropometric Indices and Body Composition in Overweight or Obese Subjects: A Systematic Review and Meta-Analysis

Purpura M, Jger R, Falk M (2021) An assessment of mutagenicity, genotoxicity, acute-, subacute and subchronic oral toxicity of paraxanthine (1,7-dimethylxanthine)

Rather than just medication alone, it focuses on sustainable, long-term results through structured education, regular check-ins, and ongoing accountability

Dont use either medication if you have a personal or family history of medullary thyroid cancer or Multiple Endocrine Neoplasia syndrome type 2