WIPI proteins serve as PI3P effectors and function as an adaptor for the lipidation machinery (ATG16L1 complex) driving membrane expansion in a PI3P-dependent manner (60, 65) ( Figure 1 , panel 2)
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Neurosteroids and their sulfated conjugates can be characterized based on their core backbone structures as pregnanes, pregnenes, androstanes, progesterones, and deoxycorticosterones
Leukopenia, macrocytosis, and thrombocytopenia occur in young adults with Down syndrome