These medicines, including liraglutide, albiglutide, dulaglutide, and semaglutide, were synthesised using strategic changes of the human GLP-1 molecule to diminish its vulnerability to DPP-4 breakdown
(7) See full prescribing information for additional drug interactions and information on interference of SYNJARDY or SYNJARDY XR with laboratory tests
Some studies have shown small reductions in total cholesterol, LDL cholesterol, and triglycerides in certain patients, though these medications are not substitutes for statins when lipid-lowering therapy is indicated
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Exenatide is available in both immediate-release (2.4-h half-life, twice-daily dosing) and extended-release formulations (approximately 2-week half-life with multiphasic profile) [27]