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10.1016/j.chmed.2023.01.004 30 ChenY.LiuY.CaoA

Wild type SOD1 can be misfolded by the aberrant translation, post-translational modification or oxidative modifications, due to the pathological conditions of the CNS environment, and produce toxic insoluble aggregates, as mutated SOD1 (Durazo et al., 2009)