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Which companies are leading these developments

Sahiner M, Yilmaz AS, Demirci S, Sahiner N

FDA identifies compounded ipamorelin acetate as raising significant safety concerns related to aggregation, peptide impurities, unnatural amino acids, immunogenicity, insufficient effectiveness, and limited safety information

Clinical trials of sermorelin did not include patients with pituitary tumors or other brain lesions causing hormone deficiencies, so safety and efficacy in this group are not established

According to endocrinology research, Sermorelin works through the GHRH pathway, the same signaling mechanism the body uses naturally